Dr. Verlander has more than thirty years of experience in biological ultrastructural research. Her research has focused on structure-function studies of the mammalian kidney, examining the structural basis for regulation of acid-base and electrolyte excretion by specific renal epithelial cells. These studies have employed transmission and scanning electron microscopy, morphometric analyses, and immunolocalization using both immunogold and immunoperoxidase techniques, and application of morphometric methods to quantify immunolabeling at both the electron microscopic and light microscopic level. She currently conducts original renal research in major collaborations with Dr. I. David Weiner, University of Florida, and Dr. Susan M. Wall, Emory University, in addition to contributing to projects with investigators at other institutions.
She is an author of numerous scientific publications in peer-reviewed journals, including the Proceedings of the National Academy of Sciences, Journal of Clinical Investigation, the American Journal of Physiology, and the Journal of the American Society of Nephrology, Hypertension, and Kidney International. In addition to original research publications, Dr. Verlander has authored or co-authored many book chapters and review articles regarding the ultrastructure of the kidney and renal physiology.
Dr. Verlander is responsible for the overall operation and scientific direction of the COM EM Core Facility and is directly involved in the day-to-day operation of the laboratory. She consults with facility users as well as with the COM EM Core technical staff to determine the best approaches to individual research questions, advises on experimental design, develops new procedures, assists users in evaluating samples, and assists in troubleshooting problems with experiments and procedures.
Dr. Matthews received her Ph.D. from the University of Florida. She has over thirty years of research experience in microscopy, including transmission and scanning electron microscopy of both animal and plant tissues and cells and immunolocalization at both the light and electron microscopic levels. She consults with users to help determine the best approach to individual projects, develops new protocols when needed, processes and sections tissue for light and electron microscopy, performs immunoperoxidase and immunogold localization experiments and morphometric analyses, and collects study images and prepares images for publications. She trains hands-on users in these procedures and the operation of the transmission electron microscope.
Chao Chen graduated from the University of Florida with a Bachelor of Science in Biology. He is primarily responsible in many aspects of light and electron microscopy work including tissue preparation, fixation, processing, sectioning, and staining. Chao assists in formulating the best methods in achieving quality results and trains users on how to use lab instruments as well as performing immuno-staining procedures. In addition, he helps collect morphometric data and prepares images for analysis and publication.